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Cardinals vs. Rams Prediction, Player Prop Bets & Odds for 10/15

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The Los Angeles Rams remain at home to continue a three-game stretch in SoFi Stadium with an NFC West battle with the Arizona Cardinals. Both teams have been more competitive than expected heading into the season, and the Rams even have a chance to get to a .500 record this weekend.

Below, you’ll find our experts’ best Cardinals vs. Rams prediction and how you can utilize a wager on any Cardinals vs. Rams odds to claim a multi-gifted DraftKings Sportsbook sign-up bonus.

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ARIZONA CARDINALS VS. LOS ANGELES RAMS PREDICTION: Rams -7 (-108 at DraftKings Sportsbook)

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Arizona Cardinals vs. Los Angeles Rams Prediction for NFL Week 6

As mentioned, neither the Cardinals nor Rams were expected to make much noise this season. However, Los Angeles has already defeated the Seattle Seahawks in the division and were within just a touchdown of the otherwise-dominant San Francisco 49ers.

Now facing an opponent that they’ve historically performed well against, backing LA is one of our favorite plays of the entire slate. We locked it in earlier this week with a friendlier point spread in this article, but we’re still willing to back the Rams as a favorite of a touchdown. We’re expecting that the worst-case scenario is a push and our wager amount refunded.

Regardless, the spread increased after the news that Arizona RB James Conner was officially being put on injured reserve. The big, physical back has quietly been one of the better rushers since coming over to the Cards from the Steelers, and with QB Kyler Murray still on the sideline, Arizona is missing its top two offensive weapons.

On the flip side, Los Angeles just got back former Super Bowl MVP WR Cooper Kupp last week, who was not limited at all as he went for 118 receiving yards on eight receptions. The Rams are also 7-2-1 against the spread when playing Arizona in the last 10 meetings, supporting our best Cardinals vs. Rams prediction on LA -7 (-108 at DraftKings Sportsbook).

Cardinals vs. Rams Player Prop Picks & Best Bets Targeting Kyren Williams & Joshua Dobbs

With the Cardinals vs. Rams odds having LA as a favorite on such a key number, you may want to make Cardinals vs. Rams best bets on different markets. If so, we have you covered with our best Cardinals vs. Rams player prop bets.

As tempting as it may be to target Kupp, we’re going to focus on RB Kyren Williams. The second-year back has looked stellar through the first five games, and has five touchdowns on the season. He’s clearly the featured back in the red zone, and even scored on the 49ers - the league’s best run defense.

The Cards are allowing 124.2 rushing yards per game, and we know that Stafford is not much of a runner himself. Therefore, we’re expecting head coach Sean McVay to feed Williams in the red zone yet again and for him to score the first touchdown (+390 at DraftKings Sportsbook) is the first of our Cardinals vs. Rams player prop bets.

That’s a great value play, and if you want to add to your Cardinals vs. Rams best bets with a more likely option, we’re also targeting Arizona QB Joshua Dobbs to go over his rushing yards prop. With Conner not by his side, he’s likely to take off more than he already has been. He had 12 rushes for 48 yards against the 49ers, and the Rams have been prone to QBs scrambling.

Philadelphia Eagles QB Jalen Hurts is the perfect example, who LA just faced last weekend and allowed him to go for 72 yards and a touchdown. Dobbs may not be Hurts, but we still like him to go over 19.5 rushing yards (-110 at DraftKings Sportsbook).

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How to Place a $5 Wager on Rams -7 at DraftKings Sportsbook to be Issued $200+

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Latest Cardinals vs. Rams Odds, Spread & Betting Lines for 10/15 Available at DraftKings

Whether you prefer our Cardinals vs. Rams prediction, Cardinals vs. Rams player props pick or a different standard market we’ve shared each of those lines and odds at DraftKings Sportsbook below:

Point spread:

  • Arizona Cardinals +7 (-112) vs. Los Angeles Rams -7 (-108)

Money line:

  • Arizona Cardinals (+260) vs. Los Angeles Rams (-325)

Total (over/under):

  • Over 49 (-108) vs. Under 49 (-112)

Joshua Dobbs rushing yards:

  • Over 19.5 (-110) vs. Under 19.5 (-110)

Kyren Williams first touchdown scorer: +390

With the prices above, a $108 wager on our Cardinals vs. Rams prediction of LA -7 profits $100 as long as they win by at least eight points. As for our Cardinals vs. Rams player prop bets, a $110 wager on Dobbs over 19.5 rushing yards profits $100 as long as he amasses 20+ yards on the ground. In terms of Williams scoring the first touchdown, a $100 wager profits $390 as long as he does so.

Rams Trade Van Jefferson to Falcons: Fallout

NFL trades don’t generally get as much attention as those in the NBA and other leagues, but the Rams did just make one of the more significant ones. With Kupp back in the fold, they felt as though WR Van Jefferson was no longer a benefit to the team.

LA got just a sixth-round pick for him, but he also played just two snaps the week before Kupp’s return. So, we’re not concerned with Jefferson’s absence affecting our Cardinals vs. Rams prediction, and you can tail our pick by joining DraftKings for your welcome offer of $200 guaranteed plus daily rewards.

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